Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-ones as potent PLK4 inhibitors with oral antitumor efficacy

Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-ones as potent PLK4 inhibitors with oral antitumor efficacy

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 19, 1 October 2016, Pages 4625-4630

Sze-Wan Li, Yong Liu, Peter B. Sampson, Narendra Kumar Patel, Bryan T. Forrest, Louise Edwards, Radoslaw Laufer, Miklos Feher, Fuqiang Ban, Donald E. Awrey, Richard Hodgson, Irina Beletskaya, Guodong Mao, Jacqueline M. Mason, Xin Wei, Xunyi Luo,