Keywords: عامل ضد تومور; Antitumor agent; Binding selectivity; Capillary zone electrophoresis; Mass spectrometry; Metallodrug;
مقالات ISI عامل ضد تومور (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Approach to ferrocenyl-podophyllotoxin analogs and their evaluation as anti-tumor agents
Keywords: عامل ضد تومور; Antitumor agent; Bioorganometallic chemistry; Ferrocene; Multi-step synthesis; Palladium; Podophyllotoxin;
Keywords: عامل ضد تومور; Green chemistry; Immobilization; Antitumor agent; Antiviral compound;
Keywords: عامل ضد تومور; Indolizine; Dimethoxytriazine; Antitumor agent; PLK1; Polo-like kinase 1 inhibitor; O-demethylation; Hilbert–Johnson transposition
Keywords: عامل ضد تومور; Annonaceous acetogenin; Antitumor agent; Convergent synthesis; Fluorescent-labeled analogue; Growth inhibitory activity
Keywords: عامل ضد تومور; Alkyne; Antitumor agent; Asymmetric synthesis; Cytotoxicity; Lipidic alkynylcarbinol;
Keywords: عامل ضد تومور; Betulinic acid derivatives; Antitumor agent; Cisplatin conjugates; Cytotoxicity; SRB assay
Keywords: عامل ضد تومور; Annonaceous acetogenins; Mimicry; Heterocycle; Antitumor agent; Fluorescent probe;
Development of novel bis-pyrazole derivatives as antitumor agents with potent apoptosis induction effects and DNA damage
Keywords: عامل ضد تومور; Synthesis; Antitumor agent; Bis-pyrazole derivatives; Apoptosis; DNA damage;
Bortezomib inhibits mammalian carbonic anhydrases
Keywords: عامل ضد تومور; Carbonic anhydrase; Boronic acid; Peptidomimetic; Antitumor agent;
Derivatives of Cucurbitacin-E-glucoside produced by Curvularia lunata NRRL 2178: Anti-inflammatory, antipyretic, antitumor activities, and effect on biochemical parameters
Keywords: عامل ضد تومور; Cucurbitacin-E-glucoside; Microbial transformation; Antitumor agent; Biochemical studies;
Convergent synthesis of stereoisomers of THF ring moiety of acetogenin thiophene analogue and their antiproliferative activities against human cancer cell lines
Keywords: عامل ضد تومور; Annonaceous acetogenin; Antitumor agent; Convergent synthesis; Growth inhibitory activity;
The discovery of novel, potent ERR-alpha inverse agonists for the treatment of triple negative breast cancer
Keywords: عامل ضد تومور; Estrogen-related receptor α; ERR-alpha; Antitumor agent; Estrogen-related receptor αinverse agonist; Triple negative breast cancer; HTLVBMKJSBOYIQ-UHFFFAOYSA-N; GEKMFGDHSAUEKC-UHFFFAOYSA-N; JDNCJZHDKRCMPJ-UHFFFAOYSA-N; FJXTYNUXLXNTMH-UHFFFAOYSA-N; SKMMZ
New indolizine–chalcones as potent inhibitors of human farnesyltransferase: Design, synthesis and biological evaluation
Keywords: عامل ضد تومور; Farnesyltransferase inhibitor; Phenothiazine; Chalcone; Indolizine; Antitumor agent
Pharmacokinetics and bioavailability of tuftsin-derived T peptide, a promising antitumor agent, in beagles
Keywords: عامل ضد تومور; Tumor immunotherapy; Tuftsin derivative; Antitumor agent; Pharmacokinetics; Bioavailability; T peptide;
Synthesis and cytotoxicity evaluation of 4â²-amino-4â²-dehydroxyloleandrin derivatives
Keywords: عامل ضد تومور; Oleandrin; Antitumor agent; Natural product; Cytotoxicity; Structure-activity relationships (SARs);
Imidazoacridinone antitumor agent C-1311 as a selective mechanism-based inactivator of human cytochrome P450 1A2 and 3A4 isoenzymes
Keywords: عامل ضد تومور; Antitumor agent; C-1311; Drug–drug interactions; Cytochrome P450 isoenzymes; Mechanism-based inhibition
Methylene versus carbonyl bridge in the structure of new tubulin polymerization inhibitors with tricyclic A-rings
Keywords: عامل ضد تومور; Tubulin inhibitor; Phenothiazine; Azaphenothiazine; Phenoxazine; Iminodibenzyl; 9(10H)Acridone; Antitumor agent;
Design, synthesis and antitumor properties of glycosylated antitumor ether lipid (GAEL)- chlorambucil-hybrids
Keywords: عامل ضد تومور; Antitumor agent; Cationic lipid; Chlorambucil-linked hybrid; Cytotoxic lipid; Glycolipid; Hybrid drug;
Characterization of a selective inverse agonist for estrogen related receptor α as a potential agent for breast cancer
Keywords: عامل ضد تومور; Estrogen related receptor α; Inverse agonist; Breast cancer xenograft; Antitumor agent; Proliferation; Migration
Molecular structure and computational studies on 2-((2-(4-(3-(2,5-dimethylphenyl)-3-methylcyclobutyl)thiazol-2-yl)hydrazono)methyl)phenol monomer and dimer by DFT calculations
Keywords: عامل ضد تومور; X-ray diffraction; IR and NMR spectroscopy; NLO; AIM; Antitumor agent
Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis
Keywords: عامل ضد تومور; 3-Ylideneoxindole; Antitumor agent; Apoptosis; Reactive oxygen species (ROS); Thioredoxin reductase (TrxR);
Novel securinine derivatives as topoisomerase I based antitumor agents
Keywords: عامل ضد تومور; Securinine derivatives; Baylis-Hillman reaction; Topoisomerase I; Antitumor agent
Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3â²-indolin]-2â²-ones as potent PLK4 inhibitors with oral antitumor efficacy
Keywords: عامل ضد تومور; Polo-like kinase 4; PLK4 inhibitors; Spiro[cyclopropane-1,3â²-indolin]-2â²-ones; (1H-Indazol-6-yl)-methylene)indolin-2-ones; Antitumor agent;
Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures
Keywords: عامل ضد تومور; Epigenetics; Histone demethylase; Lysine-specific demethylase 1; Oligoamine; Antitumor agent;
Inclusion complexes of hydroxypropyl-β-cyclodextrin with novel cytotoxic compounds: Solubility and thermodynamic properties
Keywords: عامل ضد تومور; Solubility; Inclusion complex; Antitumor agent; 2-Hydroxypropyl-β-cyclodextrin; Thermodynamics
Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors
Keywords: عامل ضد تومور; Structure-based drug design; Lead optimization; Antitumor agent; Hsp90 inhibitor
Cytotoxic cardenolides from the root bark of Calotropis gigantea
Keywords: عامل ضد تومور; Antitumor agent; Calotropis gigantea; Asclepiadaceae; Cardenolide; Cytotoxicity;
Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation
Keywords: عامل ضد تومور; PI3K inhibitors; Antitumor agent;
Site-specific PEGylation of a mutated-cysteine residue and its effect on tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)
Keywords: عامل ضد تومور; PEG-TRAIL; Site-specific PEGylation; Protein delivery; Glycosylation site; Antitumor agent;
Structure-activity relationship study of intervenolin derivatives: synthesis, antitumor, and anti-Helicobacter pylori activities
Keywords: عامل ضد تومور; Antitumor agent; Tumor-stroma interaction; Anti-Helicobacter pylori agent; Quinolone; Iminodithiocarbonate;
Design and synthesis of silicon-containing tubulin polymerization inhibitors: Replacement of the ethylene moiety of combretastatin A-4 with a silicon linker
Keywords: عامل ضد تومور; Silicon; Tubulin; Combretastatin; Colchicine; Antitumor agent;
Solvolysis and cytotoxicity of dinuclear ruthenium(II)-2,2′-bipyridine complexes with various bridged-ligands
Keywords: عامل ضد تومور; Dinuclear ruthenium(II) complexes; Solvolysis reaction; Dimethyl sulfoxide (dmso); Antitumor agent; Cytotoxicity
Synthesis and characterization of a small analogue of the anticancer natural product leinamycin
Keywords: عامل ضد تومور; DNA alkylation; Antitumor agent; Natural product
Structure–activity relationships of hybrid annonaceous acetogenins: Powerful growth inhibitory effects of their connecting groups between heterocycle and hydrophobic carbon chain bearing THF ring on human cancer cell lines
Keywords: عامل ضد تومور; Annonaceous acetogenin; Antitumor agent; Chemical synthesis; Structure–activity relationship
Involvement of cholesterol depletion from lipid rafts in apoptosis induced by methyl-β-cyclodextrin
Keywords: عامل ضد تومور; Apoptosis; Methyl-β-cyclodextrin; Cholesterol; Antitumor agent
Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines
Keywords: عامل ضد تومور; Carbonic anhydrase; Inhibitor; Isoform IX and XII; Antitumor agent; Sulfamate; Breast cancer
A water soluble tri-cationic porphyrin-EDTA conjugate induces apoptosis in human neuroendocrine tumor cell lines
Keywords: عامل ضد تومور; Cationic porphyrin; Chelator; Antitumor agent; Human neuroendocrine tumor cells; Medullary thyroid carcinoma cell lines; Small intestinal carcinoma cell lines;
Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors
Keywords: عامل ضد تومور; Structure-based drug design; Lead optimization; Macrocyclic molecule; Antitumor agent; Hsp90 inhibitor;
Palladium-catalyzed intramolecular C-H amidation: synthesis and biological activities of indolobenzazocin-8-ones
Keywords: عامل ضد تومور; Indolobenzazocinone; Benzo[d]azocinone; Pd-catalyzed C-H activation; Amidation; Antitumor agent;
Novel isoxazole polycyclic aromatic hydrocarbons as DNA-intercalating agents
Keywords: عامل ضد تومور; DNA intercalation; Antitumor agent; Docking; Polycyclic aromatic hydrocarbons; Isoxazole; 1,3-Dipolar cycloaddition
Design and synthesis of N-phenylacetyl (sulfonyl) 4,5-dihydropyrazole derivatives as potential antitumor agents
Keywords: عامل ضد تومور; Synthesis; Dihydropyrazole; Antitumor agent; Telomerase inhibitorsMTT, 3-(4,5-dimethyl-2-thiazyl)-2,5-diphenyl-2H-tetrazolium bromide; DMSO, dimethyl sulfoxide; MH, Mueller–Hinton; PBS, phosphate buffered saline; ELISA, enzymelinked immunosorbentassay; TR
Design and synthesis of C35-fluorinated solamins and their growth inhibitory activities against human cancer cell lines
Keywords: عامل ضد تومور; Annonaceous acetogenin; Structure–activity relationship; Antitumor agent; Fluorinated analogue; Chemical synthesis
Imidazolone–amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: Synthesis and biological evaluation
Keywords: عامل ضد تومور; CSI, colchicine site inhibitor; CA-4, combretastatin A-4; CA-4P, CA-4 phosphate disodium; TMP, trimethoxyphenylImidazolone–amide; Tubulin polymerization inhibitor; Antitumor agent
DNA intercalator korkormicin A preferentially kills tumor cells expressing wild type p53
Keywords: عامل ضد تومور; RPE; tert-immortalized human retinal pigment epithelial cells; PARP; poly (ADP-ribose) polymerase; Korkormicin A; DNA intercalation; p53; Apoptosis; Antitumor agent;
Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation
Keywords: عامل ضد تومور; PI polyamide; Alkylating agent; PEGylation; Minor groove binder; Antitumor agent
Synthesis, characterization and cytotoxic effect of ring-substituted and ansa-bridged vanadocene complexes
Keywords: عامل ضد تومور; Bent metallocene; Vanadocene dichloride; Cytotoxicity; Antitumor agent; X-ray structure; Leukemia
A cyclometalated diplatinum complex containing 1,1′-bis(diphenylphosphino)ferrocene as spacer ligand: Antitumor study
Keywords: عامل ضد تومور; Organoplatinum; Cyclometalation; Phosphine ligand; Antitumor agent; NMRC^N, deprotonated 2-phenylpyridine; COSY, Correlation Spectroscopy; dmso, dimethylsulfoxide; dppf, 1,1′-bis(diphenylphosphino)ferrocene; HMBC, Heteronuclear Multiple Bond Correlation;
Isoxazolidinyl polycyclic aromatic hydrocarbons as DNA-intercalating antitumor agents
Keywords: عامل ضد تومور; DNA intercalation; Antitumor agent; Docking; Polycyclic aromatic hydrocarbon; Isoxazolidine; 1,3-Dipolar cycloaddition;
Synthesis and biological evaluation of 2-indolinone derivatives as potential antitumor agents
Keywords: عامل ضد تومور; 2-Indolinones; Antitumor agent; Apoptosis; VEGFR-2ZQTYYGYOSQKTLD-LGMDPLHJSA-N; AEXSZNMNYYRMHU-PXNMLYILSA-N; HKDHBWBJGXOIKP-HBPAQXCTSA-N; QZVQRZAEPIVCQP-SDQBBNPISA-N; XTYAFZOKTXMVOZ-PTNGSMBKSA-N; RJJPMIBKEJNHDF-MLPAPPSSSA-N; JPWYNRBOBHGKDY-UVTDQMKNSA-N; GG