Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus

Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 9, 1 May 2017, Pages 2063-2068

Jiayi Xu, Songnian Lin, Robert W. Myers, Maria E. Trujillo, Michele J. Pachanski, Sunita Malkani, Hsuan-shen Chen, Zhesheng Chen, Brian Campbell, George J. Eiermann, Nadine Elowe, Brian T. Farrer, Wen Feng, Qinghong Fu, Roman Kats-Kagan, Michael Kavana,