Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2′,3′:3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGE

Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2′,3′:3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGE

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 24, 15 December 2016, Pages 5977-5984

Nagarajan Muthukaman, Sanjay Deshmukh, Neelam Sarode, Shital Tondlekar, Macchindra Tambe, Dnyandeo Pisal, Mahamadhanif Shaikh, Vidya G. Kattige, Srinivasa Honnegowda, Vikas Karande, Abhay Kulkarni, Satyawan B. Jadhav, Mahamad Yunnus A. Mahat,