Hepatoprotective hemiterpene glycosides from the rhizome of Cibotium barometz (L.) J. Sm

Five previously undescribed hemiterpene glycosides, cibotiumbarosides E−I, along with two known were isolated from the rhizome of Cibotium barometz (L.) J. Sm. Cibotiumbarosides F and I both exhibited remarkable hepatoprotective activity against APAP-induced acute liver damage in vitro, which is more effective than the positive control, bicyclol.121