Biotransformation of an africanane sesquiterpene by the fungus Mucor plumbeus

Biotransformation of 8β-hydroxy-african-4(5)-en-3-one angelate (1) gave 6α,8β-dihydroxy-african-4(5)-en-3-one 8β-angelate and 1α,8β-dihydroxy-african-4(5)-en-3-one 8β-angelate as main metabolites, and another twelve derivatives. The antifeedant and cytotoxic activities of these compounds were also investigated.86