Sesquiterpenes and other constituents of Xylaria sp. NC1214, a fungal endophyte of the moss Hypnum sp.

Xylaguaianols A−D, isocadinanol A, and 9-hydroxyxylarone, together with several known sesquiterpenes and cytochalasins were encountered in Xylaria sp. NC1214, a fungal endophyte of the moss Hypnum sp. Cytochalasin D showed significant cytotoxicity against five cancer cell lines. Cytochalasins C and Q exhibited moderate, but selective cytotoxicity.