Chemical constituents and their antibacterial and antifungal activity from the Egyptian herbal medicine Chiliadenus montanus

Phytochemical investigations of the CH2Cl2/MeOH (1:1) extract of air-dried aerial parts of Chiliadenus montanus afforded metabolites (1-8), in addition to eight previously reported compounds, two of which were isolated for the first time as free acids. Structures were established by spectroscopic methods, including HREIMS, 1H, 13C, DEPT, 1H-1H COSY, HMQC and HMBC NMR analysis. Antimicrobial activity against an array of common bacterial and fungal strains was measured via a colorimetric assay with minimal growth inhibition observed in the μg/mL range for one of the tested metabolites.