Hikiokoshins A-I, diterpenes from the leaves of Isodon japonicus

Hikiokoshins A-I, and twelve known diterpenes were isolated from leaves of Isodon japonicus (Burm. f.) H. Hara (Lamiaceae). Their structures were elucidated on the basis of spectroscopic analysis. Antimicrobial activities of hikiokoshins A and B were evaluated.