Two structurally distinct chalcone dimers from Helichrysum zivojinii and their activities in cancer cell lines

Chalcone dimers tomoroside A (1) and tomoroside B (2), along with eight known flavonoid glucosides were isolated from the aerial parts of Helichrysum zivojinii. Cell growth inhibition in cancer cell lines and modulation of mRNAs expression by novel chalcone dimers have been assessed.