Sapelenins G-J, acyclic triterpenoids with strong anti-inflammatory activities from the bark of the Cameroonian medicinal plant Entandrophragma cylindricum

► Acyclic triterpenes,sapelenins G-J (1-4) isolated from Entandrophragma cylindricum. ► Eight known compounds isolated in parallel. ► Anti-inflammatory activities evaluated by IL-17 ELISA. ► Cytotoxicity towards PBMCs also evaluated. ► Potent anti-inflammatory compound discovered.