Sesquiterpene lactones from the leaves of Hedyosmum brasiliense (Chloranthaceae)

► Sesquiterpene lactone structures were established from 1D and 2D NMR and MS data. ► The relative configurations of compounds were deduced on basis of key 1D NOE NMR experiments. ► EXSY NMR showed 7 as a compound with two isomers. ► No in vitro anti-mycobacterial activity was observed for the test lactones in the assay performed.