Aristololactams and aporphines from the stems of Fissistigma oldhamii (Annonaceae)

► Two aristololactams and three aporphines were isolated from Fissistigma oldhamii. ► Aristololactam GI is a chiral aristololactam. ► Aristololactam GI is formed by the aristololactam skeleton combining with a phenylpropanoid moiety. ► The in vitro anti-inflammatory effects of the crude extract and individual alkaloids were evaluated. ► Aristololactam GII showed potential anti-inflammatory activity.