Ajugalide-B (ATMA) is an anoikis-inducing agent from Ajuga taiwanensis with antiproliferative activity against tumor cells in vitro

► ATMA is a neoclerodane diterpenoid isolated from Ajuga taiwanensis. ► ATMA disrupts the focal adhesion complex by decreasing phosphorylation of paxillin and focal adhesion kinase (FAK). ► ATMA reduces the tumorigenic and metastatic abilities of A549 cancer cells.