An unusual caffeic acid derived bicyclic [2.2.2] octane lignan and other constituents from Cordia rufescens

► Cordia rufescens (Syn: Cordia piauhiensis) already afforded arylnaphthalene lignans. ► Bicyclic [2.2.2] octane lignan was isolated from leaves of C. rufescens. ► The isolated lignan possesses a new skeleton.