An insilico approach to structural elucidation of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Arabidopsis thaliana: Hints for herbicide design

► At N terminus are three helices which may be involved in regulation of plant enzyme. ► There are some differences in the loop regions of the At-DAHPS isozymes. ► (I/L)GAR motif in type I DAHPS is replaced by xGxR in the case of type II DAHPS. ► Motif NK(/I)PGR(/K) is present in sequences of type II DAHPS including At-DAHPS.