Norlittorine and norhyoscyamine identified as products of littorine and hyoscyamine metabolism by 13C-labeling in Datura innoxia hairy roots

► Isolation and structure confirmation of norlittorine and norhyoscyamine. ► Metabolic fate of littorine and hyoscyamine by 13C-isotopic labeling. ► Induction of norlittorine and norhyoscyamine under stress conditions. ► Proposition of norlittorine and norhyoscyamine as detoxification products.