Detoxification of cruciferous phytoalexins in Botrytis cinerea: Spontaneous dimerization of a camalexin metabolite

► Metabolism of the cruciferous phytoalexins camalexin, brassinin, cyclobrassinin, and brassilexin by the phytopathogenic fungus Botrytis cinerea. ► Antifungal activity of camalexin, brassinin, cyclobrassinin, and brassilexin against B. cinerea. ► Oxidative dimerization of 3-indolethiocarboxamide and discovery of bis-indolylthiadiazole. ► Chemical syntheses, spectroscopic characterization and antifungal activity of 3,5-(3′,3″-Bisindolyl)-1,2,4-thiadiazole.