کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5165954 | 1502415 | 2010 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Dimeric antioxidant and cytotoxic triterpenoid saponins from Terminalia ivorensis A. Chev.
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Dimeric antioxidant and cytotoxic triterpenoid saponins from Terminalia ivorensis A. Chev. Dimeric antioxidant and cytotoxic triterpenoid saponins from Terminalia ivorensis A. Chev.](/preview/png/5165954.png)
چکیده انگلیسی
Three saponins, including two dimeric triterpenoid glucosides possessing an unusual skeleton (1, 2) and a monomeric triterpenoid saponin (3) together with the known sericoside, were isolated from the bark of Terminalia ivorensis. These compounds were evaluated for their antioxidant properties and further for their cytotoxic activity against two human cancer cell lines. Compounds 2 and 3 exhibited scavenging activity against DPPH and ABTS+ radicals with IC50 values comparable with that of Trolox. Compound 1 showed antiproliferative activity against MDA-MB-231 and HCT116 human cancer cell lines with IC50 values of 3.96 and 3.43 μM, respectively.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytochemistry - Volume 71, Issues 17â18, December 2010, Pages 2108-2115
Journal: Phytochemistry - Volume 71, Issues 17â18, December 2010, Pages 2108-2115
نویسندگان
Beaudelaire Kemvoufo Ponou, Rémy Bertrand Teponno, Massimo Ricciutelli, Luana Quassinti, Massimo Bramucci, Giulio Lupidi, Luciano Barboni, Léon Azefack Tapondjou,