Diastereoisomeric macrocyclic polydisulfides from the mangrove Bruguiera gymnorrhiza

Ten-membered macrocyclic polydisulfides, trans-3,3′-dihydroxy-1,5,1′,5′-tetrathiacyclodecane (1) and its 3′-epimer (2), were isolated from the mangrove Bruguiera gymnorrhiza. Their structures were determined by spectroscopic methods and confirmed by X-ray diffraction analysis. A possible biogenetic origin was also proposed.