Absolute configuration of labdanes and ent-clerodanes from Chromolaena pulchella by vibrational circular dichroism

► Chromolaena pulchella biosynthesizes labdanes together with ent-clerodanes. ► Vibrational circular dichroism was used to assign the absolute configuration of diterpenes. ► An enantiodivergent pathway to diterpenes is present in Chromolaena pulchella.