Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin

The present study reports for the first time the production of the known compound camptothecin and its derivatives by the plant Apodytes dimidiata. Further, two fungal endophytic strains isolated from the same plant, have also been demonstrated to produce camptothecin and its derivatives, 10-hydroxycamptothecin and 9-methoxycamptothecin under in vitro conditions.