Oleanane-type triterpene oligoglycosides with pancreatic lipase inhibitory activity from the pericarps of Sapindus rarak

Oleanane-type triterpene oligoglycosides, rarasaponins I-III (1-3) and raraoside A (4) were isolated from the pericarps of Sapindus rarak DC. Among them, rarasaponins I (1, IC50 = 131 μM) and II (2, 172 μM), and raraoside A (4, 151 μM) inhibited pancreatic lipase activity.