Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators

This study demonstrated that phytocompounds from Cryptomeria japonica wood extracts possessed potent anti-inflammatory and hepatoprotective activities by attenuating proinflammatory mediator activities and CCl4- induced acute liver injury in mice. Three terpenoids (1-3) were found to be the major bioactive compounds which contributed to the observed bioactivities.