Steroidal glycosides from the underground parts of Helleborus caucasicus

Four polyhydroxylated and polyunsaturated furostanol glycosides, named caucasicosides A-D, have been isolated from the MeOH extract of the underground parts of Helleborus caucasicus. Elucidation of their structures was carried out by 2D NMR spectroscopy in combination with ESI-MS and HR-ESI-MS analyses.