UDP-glucose:(6-methoxy)podophyllotoxin 7-O-glucosyltransferase from suspension cultures of Linum nodiflorum

Cell-free protein extracts from suspension cultures of Linum nodiflorum L. (Linaceae) catalyse the 7-O-β-glucosidation of podophyllotoxin and its 6-methoxy derivative with high specificity. The enzyme activity correlates with lignan accumulation by the plant cells and is competitively inhibited by β-peltatin.