Inhibitors of phenylalanine ammonia-lyase: Substituted derivatives of 2-aminoindane-2-phosphonic acid and 1-aminobenzylphosphonic acid

(±)-2-Amino-4-bromoindane-2-phosphonic acid (2) was found as the strongest inhibitor of both phenylalanine ammonia-lyase and anthocyanin biosynthesis from a set of synthesized and evaluated compounds. Therefore, this compound and its derivatives can be valuable tool in the enzyme structure studies in a photolabelling experiments.