Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora

ent-16-Kaurene-3β,15β,ent-3-Oxo-16-kaurene-15β,18-diol (2) along with five known diterpenes were isolated from the bark of Suregada multiflora. All compounds possessed appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 μM