Five labdane diterpenoids from the seeds of Aframomum zambesiacum

Five labdane diterpenoids were isolated from the seeds of Aframomum zambesiacum along with the known labdanes, aframodial, aulacocarpin A and B, galanal A, and galanolactone and a linear sesquiterpene, nerolidol. Their structures were elucidated by spectroscopic analysis. Antiplasmodial activity against Plasmodium falciparum for some of the isolated compounds was evaluated.