Crotalic and emarginellic acids: Two triterpenes from Crotalaria emarginella and anti-inflammatory and anti-hepatotoxic activity of crotalic acid

Two triterpenes 3α-hydroxy-arbor-12-ene-28-carboxylic acid named as crotalic acid (1), and 2β,3β,21-trihydroxy-arbor-12-ene-29-carboxylic acid, named as emarginellic acid (2) were obtained from Crotalaria emarginella. The crotalic acid 1 exhibited 53% anti-inflammatory activity with respect oxyphenyl butazone (69%), and 30% anti-hepatotoxic activity with respect silybon-70 (57%).