Vasodilatory and hypoglycaemic effects of two pyrano-isoflavone extractives from Eriosema kraussianum N. E. Br. [Fabaceae] rootstock in experimental rat models

Two pyrano-isoflavones (e.g., 1) produced dose-related initial transient contractions followed by secondary longer-lasting significant relaxation of rat isolated portal veins. The two compounds also caused dose-dependent hypoglycaemia in rats.