Tirucallane triterpenes from the roots of Ozoroa insignis

Eight tirucallane triterpenes, methyl 3α,24S-dihydroxytirucalla-8,25-dien-21-oate, methyl 3α-hydroxy-24-oxotirucalla-8,25-dien-21-oate, methyl 3α-hydroxy-25,26,27-trinor-24-oxotirucall-8-en-21-oate, 3α,25-dihydroxy-24-(2-hydroxyethyl)-tirucall-8-en-21-oic acid, 3α,24S,25-trihydroxytirucall-8-en-21-oic acid, 3α,24R,25-trihydroxytirucall-8-en-21-oic acid, 3α,25-dihydroxytirucall-8-en-21-oic acid, and methyl 3α,25-dihydroxytirucall-8-en-21-oate, together with α-elemolic acid methyl ester, were isolated from the roots of Ozoroa insignis. Their structures were elucidated on the basis of spectroscopic evidence.