کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5176858 1380842 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New β-carboline and indole alkaloids from Actinomycete Actinomadura sp. BCC 24717
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
New β-carboline and indole alkaloids from Actinomycete Actinomadura sp. BCC 24717
چکیده انگلیسی


- The constituents of actinomycete Actinomadura sp. BCC 24717 were investigated.
- Four new β-carbolines 1-4 and two new indoles 5-6 were isolated.
- The structures of new compounds were elucidated and their biological activities were also evaluated.
- Compound 4 exhibited cytotoxicity to Vero cells, while 6 showed antifungal activity

Four new β-carbolines 1-4 and two new indoles 5-6 were isolated together with thirteen known compounds from actinomycete, Actinomadura BCC 24717. Structures of the new compounds, 1-6, were determined by NMR spectroscopic and MS spectrometric analyses. Compound 4 exhibited cytotoxicity to Vero cells and compound 6 showed antifungal activity with IC50 35.91 μg/mL and 41.97 μg/mL, respectively.

Chemical structures of compounds 1, 2, and 5

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytochemistry Letters - Volume 6, Issue 3, August 2013, Pages 491-494
نویسندگان
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