Two secopregnane-type steroidal glycosides from Cynanchum stauntonii (Decne.) Schltr.ex Levl.

► This study reports on isolation of two new steroid glycosides (1 and 2) from the roots extract of Cynanchum stauntonii (Decne.) Schltr.ex Levl. ► Their structures were elucidated on the basis of 1D- and 2D-NMR, mass, IR and UV spectroscopic analyses. ► Na+/K+-ATPase inhibitory activity was tested for 1 and 2, and they showed moderate activity.