کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5177071 | 1380848 | 2012 | 6 صفحه PDF | دانلود رایگان |
The effective method of isolation, separation and purification of (â)-α- and (+)-β-thujone (1a and 1b) from Thuja occidentalis was elaborated. Chemical (m-CPBA) and microbial Baeyer-Villiger oxidation of (â)-α- and (+)-β-thujone was carried out. Four new bicyclic δ-lactones (2a, 2b, 3a and 3b) with condensed cyclopropane ring were obtained.
The four new bicyclic δ-lactones with condensed cyclopropane ring were obtained from α- and β-thujone. Both isomers of thujone were isolated from white cedar leaves oil (Thuja occidentalis).Highlights⺠The monoterpenoid ketones: α- and β-thujone were isolated from Thuja occidentalis essential oil. ⺠Chemical and microbial oxidation of α- and β-thujone afforded four new δ-lactones with condensed cyclopropane ring. ⺠The crystal structures of three new lactones are reported.
Journal: Phytochemistry Letters - Volume 5, Issue 2, June 2012, Pages 340-345