Antimicrobial metabolites from the aquatic fungus Delitschia corticola

► The present studies represent the first reported chemical examination of D. corticola. ► From the culture broth of the aquatic fungus Delitschia corticola YMF1.01111, two new metabolites, (3S, 4S, 5S, 6R)-4,5,6-trihydroxy-3-methyl-3,4,6,7-tetrahydro-1H-isochromen-8 (5H)-one (1) and (3R, 4S)-7-ethyl-3,4,6,8-tetrahydroxy-3,4-dihydronaphthalen-1(2H)-one (2), were isolated with four known ones. ► The six metabolites were examined in vitro for antimicrobial activities against a panel of bacteria and fungi.