Metabolites from Penicillium sp., an endophytic fungus from the liverwort Riccardia multifida (L.) S. Gray

► The first report of a new isocoumarin derivative and a funicone-related compound from endophytic fungus. ► The first report of metabolites of endophytic fungus isolated from liverwort. ► Compounds 2 and 4 exhibited significant inhibitory activities against the growth of germination of Arabidopsis thaliana seeds.