Flavonol glycosides with lipid accumulation inhibitory activity from Sedum sarmentosum

► Three new flavonol glycosides, sarmenosides V-VII, were isolated from the whole plant of Sedum sarmentosum. ► Several flavonoid constituents were found to show strong lipid accumulation inhibitory activity. ► The activity of sarmenoside V was stronger than that of a PPAR-α agonist, bezafibrate.