Antidiabetic activity of phenolic compounds from Pecan bark in streptozotocin-induced diabetic rats

► Seven phenolic compounds were characterized from bark of Pecan tree; two of them are new and the others are known. ► Hypoglycemic, antioxidant and aldose reductase inhibitory effect in lenses of diabetic rats were evaluated for the compounds. ► Compound 3 and its glucoside 7 revealed the highest hypoglycaemic and AR-inhibitory effects.