2β-Acetoxyferruginol-A new antibacterial abietane diterpene from the bark of Prumnopitys andina

A new antibacterial abietane diterpene, 2β-acetoxyferruginol (1) was isolated from the stem bark of Prumnopitys andina and its structure was determined by spectral means. Activity was assessed against multidrug and methicillin-resistant Staphylococcus aureus (MRSA) strains and with Propionibacterium acnes, the major bacterial cause of acne, and the minimum inhibitory concentration value against P. acnes was 4 μg/ml.