کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5185186 | 1381070 | 2010 | 8 صفحه PDF | دانلود رایگان |
In order to develop a non toxic and biocompatible hydrogel system with potential ability in biotechnology, modified photo-crosslinkable hydrogel membranes based on chitosan were prepared. Using an EDC/NHS conjugation method, chitosan was chemically modified to incorporate a photosensitive α-cyano-4-hydroxycinnamic acid moiety with various degrees of substitutions. Fourier transform infrared spectra (FTIR), proton nuclear magnetic resonance (1H NMR) and ultraviolet-visible light spectra (UV-vis) were used for structural characterization of modified chitosan, The obtained membranes were crosslinked by irradiation in the ultraviolet region, where the photosensitive monomers showed maximum sensitivity. The prepared photo-crosslinked hydrogel membranes were investigated by thermal gravimetric analysis (TGA) and wide angle X-ray diffraction (WAXD). The swelling behaviors were investigated in terms of pH, time of swelling, and degree of substitution. Also, mechanical properties of the different photo-crosslinked hydrogel membranes were studied in both dry and wet conditions.
Journal: Polymer - Volume 51, Issue 5, 2 March 2010, Pages 1002-1009