کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5185439 | 1381077 | 2010 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fabrication and characterization of 3-dimensional PLGA nanofiber/microfiber composite scaffolds
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Novel three-dimensional (3-D) nano-/microfibrous poly(lactic-co-glycolic acid) (PLGA) scaffolds were fabricated by hybrid electrospinning, involving a combination of solution electrospinning and melt electrospinning. The scaffolds consisted of a randomly oriented structure of PLGA microfibers and PLGA nanofibers. The cell attachment and spreading of normal human epidermal keratinocytes (NHEK) and fibroblasts (NHEF) were several times higher in the PLGA nano-/microfiber composite scaffolds than in the microfibrous scaffolds without nanofibers. This shows that the presence of nanofibers enhanced the attachment and spreading of the cells on the nano-/microfiber composite scaffolds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Polymer - Volume 51, Issue 6, 11 March 2010, Pages 1320-1327
Journal: Polymer - Volume 51, Issue 6, 11 March 2010, Pages 1320-1327
نویسندگان
Sung Jin Kim, Da Hyun Jang, Won Ho Park, Byung-Moo Min,