New copolymers of N,N-dimethylacrylamide with blocked isocyanates for oligonucleotide immobilization in DNA microarray technology

Finally, some model microarrays were fabricated by spotting and hybridization with complementary, fluorescently labelled targets was carried out. It resulted in surfaces coated with copolymers which show well defined circular spots with a fluorescence intensity higher than that obtained by slides treated by silanization, and based on the same immobilization chemistry.