کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5190146 | 1381199 | 2007 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of a functionalized polythiophene as an active substrate for a label-free electrochemical genosensor
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis of a functionalized polythiophene as an active substrate for a label-free electrochemical genosensor Synthesis of a functionalized polythiophene as an active substrate for a label-free electrochemical genosensor](/preview/png/5190146.png)
چکیده انگلیسی
The synthesis of a new functionalized terthiophene monomer with an unsaturated side chain, 3-((2â²:2â³,5â³:2â´-terthiophene)-3â³-yl) acrylic acid, is described. A conducting polymer was obtained by electropolymerization of the functionalized monomer. The properties of the polymer were investigated using FT-IR, Raman and UV-vis spectroscopy. The application of the polymer as an active substrate for a genosensor is demonstrated by the covalent attachment of amino-end modified oligonucleotide probes to the carboxylic acid group of the polymer. The hybridization of the complementary ODNs can be clearly detected by an increase in the admittance without the need for an indicator or any sample modifications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Polymer - Volume 48, Issue 12, 4 June 2007, Pages 3413-3419
Journal: Polymer - Volume 48, Issue 12, 4 June 2007, Pages 3413-3419
نویسندگان
Hui Peng, Lijuan Zhang, John Spires, Christian Soeller, Jadranka Travas-Sejdic,