کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5207958 | 1503000 | 2016 | 102 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The use of polymer-based nanoparticles and nanostructured materials in treatment and diagnosis of cardiovascular diseases: Recent advances and emerging designs
ترجمه فارسی عنوان
استفاده از نانوذرات مبتنی بر پلیمر و مواد نانوساختار در درمان و تشخیص بیماریهای قلبی عروقی: پیشرفت های اخیر و طرح های در حال ظهور
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
چکیده انگلیسی
This review summarizes important advances in polymer-based nanotechnologies for the treatment and diagnosis of cardiovascular diseases, focusing on nanoparticles and nanostructured materials/devices. The current state of the art and design parameters are discussed with the aim of providing a source of information that can aid in the development of new treatments by bridging between materials development, preclinical, and clinical trials. This is highly relevant as cardiovascular diseases remain a leading cause of death worldwide and as current treatments burden the healthcare systems with great costs. Different strategies, from targeting theranostic nanocarriers, to dual-drug depot systems, injectable cell scaffolds, and LDL acceptors are treated. The review ends with a concluding outlook on the possibilities and challenges presented to polymer-based nanotechnologies in cardiovascular disease therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Polymer Science - Volume 57, June 2016, Pages 153-178
Journal: Progress in Polymer Science - Volume 57, June 2016, Pages 153-178
نویسندگان
Yen-Jen Wang, Mikael Larsson, Wei-Ting Huang, Shih-Hwa Chiou, Stephen J. Nicholls, Jui-I Chao, Dean-Mo Liu,