کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5211695 1382969 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Peptide imprinted polymer synthesized by radiation-induced graft polymerization
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Peptide imprinted polymer synthesized by radiation-induced graft polymerization
چکیده انگلیسی

The design of polymer surfaces with molecular recognition capabilities is an exciting subject with potential application in the analytical and biotechnological fields. Molecular imprinted polymers (MIPs) are still in their infancy and new methodologies are required to broaden their application. In this paper, MIPs were synthesized by simultaneous radiation-induced graft polymerisation in a polar medium. Bacitracin, a cyclic decapeptide, was used as the target molecule to develop MIP grafted onto macroporous membranes. Soluble ternary complexes of vinyl pyridine, bacitracin and copper (II) were obtained and characterized by visible spectroscopy in an aqueous medium. These complexes were grafted onto macroporous polyethylene membranes. MIP materials showed ability to adsorb bacitracin in a higher amount than non-printed polymers. In addition, these materials showed a 5-fold greater selectivity to bacitracin than that of chemically modified bacitracins.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reactive and Functional Polymers - Volume 66, Issue 11, November 2006, Pages 1199-1205
نویسندگان
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