کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5212037 | 1383101 | 2017 | 6 صفحه PDF | دانلود رایگان |
By virtue of high affinity of Gadolinium(III) with fluoride, a novel MRI/fluorescence bimodal probe was prepared by self-assembly of Gd(III) based contrast agent with the coumarin-based fluorophore (CL). Upon addition of fluoride ion (Fâ) to the aqueous solution of EDTA-Gd(III)-CL, the replacement of coordination CL occurs, realizing switch-on both the longitudinal relaxivity (r1) and fluorescence responses, simultaneously. The fluorescence detection limit for fluoride ions was established at 0.15 μM. EDTA-Gd(III)-CL features of favorable selectivity towards Fâ for both relaxivity and fluorescence, reliability at physiological pH allow its potential application in biomedical diagnosis fields.
A fluoride-specific MRI/fluorescence bimodal probe was reported.203
Journal: Tetrahedron - Volume 73, Issue 38, 21 September 2017, Pages 5700-5705