کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5212124 | 1383105 | 2017 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Biomimetic synthesis of myrtucommulone K, N and O
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A concise total synthesis of myrtucommulone K, N and O have been developed in 4 steps from commercially available materials. The synthetic strategy was inspired primarily by the biogenetic hypothesis and firstly enabled via a reduction, dehydration sequence for preparing isobutylidenesyncarpic acid followed by a hetero-Diels-Alder reaction to disclose the target moleculars. In this approach the exocyclic double bond of (−)-β-caryophyllene was more active than the endocyclic one in hetero-Diels–Alder reaction as the dienophile. The route is protecting-group-free, concise step, redox and pot economy.
Figure optionsDownload high-quality image (185 K)Download as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 73, Issue 26, 29 June 2017, Pages 3691–3695
Journal: Tetrahedron - Volume 73, Issue 26, 29 June 2017, Pages 3691–3695