Combination of the fluorescent conjugated polymer and 1, 4, 7, 10- tetraazacyclododecane-1, 4, 7-triacetic acid gadolinium chelate as an agent for dual-modal imaging

The instructions of the box below: The side chains of the fluorescent conjugated polymer PPV-NMe3+ were modified with 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7-triacetic acid gadolinium chelate (DO3A-Gd) units through 'Cu (I)-catalyzed azide-Alkyne Cycloaddition (CuAAC)' reactions, which a kind of 'click reaction'. The final product, PPV-NMe3+-DO3A-Gd, can achieve dual-modal Fluorescent/MR imaging.