AIBN-promoted amidation of anilines with 1, 3-diketones via oxidative cleavage of C-C bond under aerobic conditions

N-Acylation of anilines with 1, 3-diketones promoted by AIBN (2-2′-azoisobutyronitrile) under metal-free and peroxide-free conditions in the presence of molecular oxygen as oxidant has been described. This protocol proceeds by the oxidative cleavage of C-C bond with simultaneous intermolecular C-N bond formation under mild conditions.

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